Hydrogel Microspheres Empowering Organ‐on‐a‐Chip Systems: Innovations and Applications (Small 44/2025)
Jiacheng Liu, Chengcheng Du, Jinping Chen, Bochen Tang, Senrui Liu, Jianye Tan, Xuefeng Luo, Jingdi Zhan, Junyan Liu, Zhuolin Chen, Yichi Zhang, Zhong Li, Wei Huang, Yiting Lei
Abstract
Organ-on-a-Chip Organ-on-a-chip (OoC) uses microfluidic technology to replicate human organ environments for modelling physiology, diseases, drug development, and personalized medicine. Recent advances in hydrogel microspheres enhance OoC, mimicking extracellular matrix properties, simulating complex microenvironments, and enabling better intercellular and inter-organ crosstalk. More in article number 2504563, Zhong Alan Li, Wei Huang, Yiting Lei, and co-workers.
Topics & Concepts
MicrosphereNanotechnologyMicrofluidicsMaterials scienceDrug deliverySelf-healing hydrogelsExtracellular matrixBiomedical engineeringPersonalized medicineTargeted drug deliveryExtracellular vesiclesComputer scienceMatrix (chemical analysis)Biomimetic materialsBiofabricationComplex matrix3D Printing in Biomedical ResearchTissue Engineering and Regenerative MedicineInnovative Microfluidic and Catalytic Techniques Innovation