Predicting Electrophoretic Mobility of Proteoforms for Large-Scale Top-Down Proteomics
Daoyang Chen, Rachele A. Lubeckyj, Zhichang Yang, Elijah N. McCool, Xiaojing Shen, Qianjie Wang, Tian Xu, Liangliang Sun
Abstract
. Our results also indicate that N-terminal acetylation and phosphorylation both decrease the proteoforms' charge by roughly one charge unit.
Topics & Concepts
ChemistryCapillary electrophoresisProteomicsComputer scienceChromatographyBiochemistryGeneAdvanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and ApplicationsBiosensors and Analytical Detection