Current progress and novel strategies that target CDK12 for drug discovery
Peng Lei, Jifa Zhang, Pei‐Yu Liao, Changyu Ren, Jiaxing Wang, Di Wang
Topics & Concepts
Drug discoveryDNA damageDrug developmentDNA repairSynthetic lethalityBiologyComputational biologyCancer researchDrugChemistryBioinformaticsGeneticsDNAPharmacologyProtein Degradation and InhibitorsAdvanced Breast Cancer TherapiesUbiquitin and proteasome pathways