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Assessment of Phase 3 Randomized Clinical Trials Including Patients With Leptomeningeal Disease

Alisha Sharma, Kathryn Corbett, Hany Soliman, Arjun Sahgal, Sunit Das, Mary Jane Lim-Fat, Katarzyna J. Jerzak

2023JAMA Oncology16 citationsDOIOpen Access PDF

Abstract

This systematic review examines the proportion of patients with leptomeningeal disease included in phase 3 randomized clinical trials for patients with metastatic breast cancer, lung cancer, and melanoma.

Topics & Concepts

MedicineRandomized controlled trialBreast cancerLung cancerDiseaseClinical trialMelanomaCancerInternal medicineOncologyCancer researchBrain Metastases and TreatmentGlioma Diagnosis and TreatmentCancer Treatment and Pharmacology
Assessment of Phase 3 Randomized Clinical Trials Including Patients With Leptomeningeal Disease | Litcius