Discovery of highly potent proapoptotic antiestrogens in a series of androst-5,16-dienes D-modified with imidazole-annulated pendants

V. E. Birukova, Alexander M. Scherbakov, Anastasia A. Ilina, Diana I. Salnikova, Olga E. Andreeva, Yaraslau Dzichenka, И. В. Заварзин, Yulia A. Volkova

2023The Journal of Steroid Biochemistry and Molecular Biology10 citationsDOI

Topics & Concepts

ChemistrySteroidEstrogen receptorDocking (animal)Estrogen receptor alphaImidazoleStereochemistryCytotoxicityBiochemistryBreast cancerCancerIn vitroHormoneInternal medicineMedicineNursingEstrogen and related hormone effectsComputational Drug Discovery MethodsPharmacogenetics and Drug Metabolism