Therapeutic efficacies of mitochondria-targeted esculetin and metformin in the improvement of age-associated atherosclerosis via regulating AMPK activation
Sriravali Pulipaka, Gajalakshmi Singuru, Shashikanta Sahoo, Altab Shaikh, Rajamannar Thennati, Srigiridhar Kotamraju
Topics & Concepts
MetforminAMPKSenescenceMedicineInflammationMitochondrionMitochondrial ROSPharmacologyInternal medicineEndocrinologyDiabetes mellitusCancer researchOxidative stressBiologyCell biologyPhosphorylationProtein kinase ASirtuins and Resveratrol in MedicineAntioxidant Activity and Oxidative StressAutophagy in Disease and Therapy