Midlife aerobic exercise and dynamic cerebral autoregulation: associations with baroreflex sensitivity and central arterial stiffness
Tsubasa Tomoto, Justin Repshas, Rong Zhang, Takashi Tarumi
Abstract
Middle-aged athletes (MA) showed intact dynamic cerebral autoregulation (dCA) during sit-stand maneuvers when compared with young (YS) and middle-aged sedentary (MS) adults. Conversely, MA showed the significant attenuation of age-related carotid distensibility and baroreflex sensitivity (BRS) impairments. In MA and YS groups, BRS was positively associated with dCA gain at rest and carotid distensibility. Our findings suggest that midlife aerobic exercise improves BRS by reducing central arterial stiffness, which contributes to CBF regulation through dCA.
Topics & Concepts
BaroreflexArterial stiffnessMedicineCardiologyCerebral autoregulationAutoregulationAerobic exerciseInternal medicineBlood pressureAnesthesiaHeart rateHeart Rate Variability and Autonomic ControlTraumatic Brain Injury and Neurovascular DisturbancesCardiovascular Health and Disease Prevention