FGFR leads to sustained activation of STAT3 to mediate resistance to EGFR-TKIs treatment
Xiaoping Song, Wei Tang, Hui Peng, Xin Qi, Jing Li
Topics & Concepts
GefitinibCancer researchEpidermal growth factor receptorSTAT3Tyrosine kinasePhosphorylationSignal transductionCancerBiologyMedicineCell biologyInternal medicineLung Cancer Treatments and MutationsCytokine Signaling Pathways and InteractionsProtein Tyrosine Phosphatases