Palladium-Catalyzed Thiocarbonylation of Alkenes toward Linear Thioesters

Abstract

Thiocarbonylation of alkenes offers an ideal procedure for the synthesis of thioesters. However, thiocarbonylation of alkenes, especially styrenes, to produce valuable linear thioesters has remained a challenge. In this Letter, a general palladium-catalyzed thiocarbonylation of alkenes to produce linear thioesters has been achieved. Moderate to good yields of desired thioesters can be produced from readily available alkenes in a straightforward manner.

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