Genomic Basis of Occurrence of Cryptic Resistance among Oxacillin- and Cefoxitin-Susceptible <i>mecA</i> -Positive Staphylococcus aureus
Bingshao Liang, Zhile Xiong, Zhuwei Liang, Chao Zhang, Hao Cai, Yan Long, Fei Gao, Jielin Wang, Qiulian Deng, Huamin Zhong, Yongqiang Xie, Lianfen Huang, Sitang Gong, Zhenwen Zhou
Abstract
The oxacillin- and cefoxitin-susceptible mecA -positive Staphylococcus aureus is a novel type of “stealth” methicillin-resistant S. aureus (MRSA), which is difficult to be detected using conventional methods. To investigate the genomic basis of their occurrence, we sequenced the whole genome of two previously recovered oxacillin- and cefoxitin-susceptible mecA -positive MRSA isolates from breast abscesses in a lactating woman and a nasal swab of a healthy student in Guangzhou.
Topics & Concepts
CefoxitinStaphylococcus aureusSCCmecMicrobiologyBiologyPenicillinGeneMethicillin-resistant Staphylococcus aureusGeneticsAntibioticsBacteriaAntimicrobial Resistance in StaphylococcusBacterial biofilms and quorum sensingAntimicrobial Peptides and Activities