Qingluotongbi formula regulates the LXRα-ERS-SREBP-1c pathway in hepatocytes to alleviate the liver injury caused by Tripterygium wilfordii Hook. f.
Zhichao Yu, Zhe Feng, Ling Fu, Jing Wang, Changqing Li, Huaxu Zhu, Tong Xie, Jie Zhou, Lingling Zhou, Xueping Zhou
Topics & Concepts
Tripterygium wilfordiiLiver X receptorLiver injuryDownregulation and upregulationIn vivoBiologySterol regulatory element-binding proteinLipid dropletHepatocyteAgonistInternal medicinePharmacologyEndocrinologyReceptorIn vitroBiochemistrySterolCholesterolMedicineNuclear receptorPathologyGeneTranscription factorBiotechnologyAlternative medicineNatural Compounds in Disease TreatmentDrug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology