Access to functionalized alkynylcyclopropanes <i>via</i> reductive radical-polar crossover-based reactions of 1,3-enynes with alkyl radicals
Beibei Zhang, Junfei Luo, Yewen Fang
Abstract
Using SET reduction as the key process, functionalized alkynylcyclopropanes could be accessed via the reactions of 1,3-enynes with alkyl radicals enabled by photoredox or nickel catalysis.
Topics & Concepts
ChemistryRadicalAlkylPolarCrossoverMedicinal chemistryCombinatorial chemistryOrganic chemistryPhysicsAstronomyComputer scienceArtificial intelligenceCyclopropane Reaction MechanismsCatalytic C–H Functionalization MethodsRadical Photochemical Reactions