Activation of apoptosis by rationally constructing NIR amphiphilic AIEgens: surmounting the shackle of mitochondrial membrane potential for amplified tumor ablation
Haidong Li, Lu Yang, Jeewon Chung, Jingjing Han, Heejeong Kim, Qichao Yao, Gyoungmi Kim, Xiaofeng Wu, Saran Long, Xiaojun Peng, Juyoung Yoon
Abstract
was successfully applied to kill cancer cells and to efficiently inhibit tumor growth in mice. This study will provide a new avenue for researchers to design more ideal amphiphilic AIE photosensitizers with NIR fluorescence.
Topics & Concepts
ShackleAmphiphileAblationApoptosisChemistryBiophysicsNanotechnologyMaterials scienceBiochemistryBiologyOrganic chemistryEngineeringCopolymerPolymerAerospace engineeringStructural engineeringNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsAdvanced biosensing and bioanalysis techniques