High-dose VitC plus oncolytic adenoviruses enhance immunogenic tumor cell death and reprogram tumor immune microenvironment
Jinhu Ma, Chunxue Zhang, Gang Shi, Dan Yue, Yongheng Shu, Shichuan Hu, Zhongbing Qi, Yanwei Chen, Bin Zhang, Yong Zhang, Anliang Huang, Chao Su, Yan Zhang, Hongxin Deng, Ping Cheng
Topics & Concepts
Oncolytic virusImmunogenic cell deathImmune systemTumor microenvironmentCD8Cancer researchOncolytic adenovirusCombination therapyProgrammed cell deathT cellApoptosisMedicineImmunotherapyChemistryImmunologyPharmacologyBiochemistryVirus-based gene therapy researchCAR-T cell therapy researchViral gastroenteritis research and epidemiology