Relationship Between Melatonin and Cardiovascular Disease
Flora Özkalaycı, Umut Kocabaş, Betül Uğur Altun, Seithikurippu R. Pandi‐Perumal, Armağan Altun
Abstract
Coronary artery disease (CAD) is one of the leading causes of morbidity and mortality worldwide. The coronary atherosclerotic process involves different pathological mechanisms; inflammation is one of the major triggers for the development of atherosclerotic plaque. Although several studies showed the favorable effects of melatonin on the cardiovascular system (CVS), melatonin seems not to take its rightful place in today's clinical practice. This review aims to point out the role of melatonin on cardiovascular disease (CVD) and its' risk factors. All data were obtained via PubMed, Wikipedia, and Google.
Topics & Concepts
MelatoninDiseaseMedicineInternal medicineCircadian rhythm and melatoninSpaceflight effects on biologyHeart Rate Variability and Autonomic Control