Endothelial Progenitor Cells: An Appraisal of Relevant Data from Bench to Bedside
Doralisa Morrone, Maria Elena Lucia Picoi, Francesca Felice, Andrea De Martino, Cristian Scatena, Paolo Spontoni, Antonio Giuseppe Naccarato, Rossella Di Stefano, Uberto Bortolotti, Massimo Dal Monte, Stefano Pini, Marianna Abelli, Alberto Balbarini
Abstract
The mobilization of endothelial progenitor cells (EPCs) into circulation from bone marrow is well known to be present in several clinical settings, including acute coronary syndrome, heart failure, diabetes and peripheral vascular disease. The aim of this review was to explore the current literature focusing on the great opportunity that EPCs can have in terms of regenerative medicine.
Topics & Concepts
Progenitor cellMedicineRegenerative medicineDiabetes mellitusBone marrowBench to bedsideIntensive care medicineBioinformaticsStem cellImmunologyBiologyCell biologyEndocrinologyMedical physicsAngiogenesis and VEGF in CancerLymphatic System and DiseasesMesenchymal stem cell research