Differential reduction of gray matter volume with age in 35 cortical areas in men (more) and women (less)
Peka Christova, Apostolos P. Georgopoulos
Abstract
This study showed an overall decrease of cortical gray matter with age but with different rates of volume reduction in different areas, with smaller decrease rates in women than in men. The highest volume reduction rate was observed for the rostral anterior cingulate cortex, an area linked to depression. These findings could serve as a normative reference for clinical conditions that manifest with abnormal brain atrophy.
Topics & Concepts
AtrophyBrain sizeCingulate cortexPsychologyAnterior cingulate cortexCerebral cortexGrey matterCortex (anatomy)NeuroscienceWhite matterAnatomyMedicineAudiologyInternal medicineCentral nervous systemMagnetic resonance imagingCognitionRadiologyFunctional Brain Connectivity StudiesAdvanced Neuroimaging Techniques and ApplicationsAdvanced MRI Techniques and Applications