Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1
Mengqi Li, Chen‐Song Zhang, Jin-Wei Feng, Xiaoyan Wei, Cixiong Zhang, Changchuan Xie, Yaying Wu, Simon A. Hawley, Abdelmadjid Atrih, Douglas J. Lamont, Zhichao Wang, Hai-long Piao, D. Grahame Hardie, Sheng‐Cai Lin
Abstract
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Topics & Concepts
BiologymTORC1Aldolase AAMPKBiochemistryCell biologyComputational biologyKinaseSignal transductionEnzymeProtein kinase API3K/AKT/mTOR pathwayMetabolism, Diabetes, and CancerCancer, Hypoxia, and MetabolismPancreatic function and diabetes