Control of Foxp3 induction and maintenance by sequential histone acetylation and DNA demethylation
Jun Li, Beisi Xu, Ming-Hong He, Xinying Zong, Trevor Cunningham, Cher Sha, Yiping Fan, Richard Cross, Jacob H. Hanna, Yongqiang Feng
Abstract
cell lineage specification.
Topics & Concepts
AcetylationHistoneDNA demethylationChromatinCell biologyEpigeneticsBiologyTranscription factorEnhancerFOXP3Transcriptional regulationDNA methylationDNAChemistryMolecular biologyGeneticsGene expressionGeneImmune systemT-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune Responses