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Virology, Epidemiology, Pathogenesis, and Control of COVID-19

Yuefei Jin, Haiyan Yang, Wangquan Ji, Weidong Wu, Shuaiyin Chen, William Zhang, Guangcai Duan

2020Viruses1,632 citationsDOIOpen Access PDF

Abstract

The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) in China has been brought to global attention and declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Scientific advancements since the pandemic of severe acute respiratory syndrome (SARS) in 2002~2003 and Middle East respiratory syndrome (MERS) in 2012 have accelerated our understanding of the epidemiology and pathogenesis of SARS-CoV-2 and the development of therapeutics to treat viral infection. As no specific therapeutics and vaccines are available for disease control, the epidemic of COVID-19 is posing a great threat for global public health. To provide a comprehensive summary to public health authorities and potential readers worldwide, we detail the present understanding of COVID-19 and introduce the current state of development of measures in this review.

Topics & Concepts

PandemicMiddle East respiratory syndromeEpidemiologyOutbreakPublic healthCoronavirus disease 2019 (COVID-19)DiseaseMedicineCoronavirusGlobal healthVirologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Intensive care medicineImmunologyEnvironmental healthInfectious disease (medical specialty)PathologyCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchCOVID-19 and Mental Health