Sensing of mitochondrial DNA by ZBP1 promotes RIPK3-mediated necroptosis and ferroptosis in response to diquat poisoning
Kunmei Lai, Junjie Wang, Siyi Lin, Zhimin Chen, Guo Lin, Keng Ye, Ying Yuan, Yujiao Lin, Chuan‐Qi Zhong, Jianfeng Wu, Huabin Ma, Yanfang Xu
Topics & Concepts
NecroptosisCell biologyDNA damageProgrammed cell deathProtein kinase ABiologyKinasePhosphorylationMitochondrial DNAMitochondrionCancer researchDNAApoptosisBiochemistryGeneFerroptosis and cancer prognosisEpigenetics and DNA Methylationinterferon and immune responses