Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP)
F Antoni, Manuel Bause, Matthias Scholler, Stefanie Bauer, Simone Stark, Scott M. Jackson, Ioannis Manolaridis, Kaspar P. Locher, Burkhard König, Armin Buschauer, Günther Bernhardt
Topics & Concepts
ChemistryAbcg2MoietyClick chemistryCombinatorial chemistryStereochemistryAmideATPasePotencyEnzymeIn vitroBiochemistryTransporterATP-binding cassette transporterGeneDrug Transport and Resistance MechanismsCancer therapeutics and mechanismsHIV/AIDS drug development and treatment