Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome
Ji Geng, Tejinder Pal Khaket, Jie Pan, Wen Li, Yan Zhang, Yong Ping, Maria Inmaculada Cobos Sillero, Bingwei Lu
Topics & Concepts
BiologyEndoplasmic reticulumCell biologyMitochondrionFragile X syndromeHomeostasisVoltage-dependent anion channelVDAC1Calcium signalingFMR1Calcium metabolismCalciumSignal transductionBiochemistryGeneticsFragile xInternal medicineGeneEscherichia coliMedicineBacterial outer membraneGenetics and Neurodevelopmental DisordersMitochondrial Function and PathologyEndoplasmic Reticulum Stress and Disease