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<scp><i>YY1</i></scp>‐Related Dystonia: Clinical Aspects and Long‐Term Response to Deep Brain Stimulation

Giovanna Zorzi, Ignacio Juan Keller Sarmiento, Federica Rachele Danti, Bernabé I. Bustos, Federica Invernizzi, Celeste Panteghini, Chiara Reale, Barbara Garavaglia, Luisa Chiapparini, Steven Lubbe, Nardo Nardocci, Niccolò E. Mencacci

2021Movement Disorders27 citationsDOI

Abstract

Video S1. Patient at age 17 years before DBS; he has severe generalized dystonia with continuous dystonic movement at rest and prominent trunk involvement exacerbated by walking. After DBS at 3-year follow-up, mobile dystonia at rest and trunk dystonia are considerably reduced. Laryngeal dystonia is evident on speech. At 15-year follow-up DBS efficacy on trunk and mobile dystonia is still evident, although less prominent, and laryngeal dystonia persisted. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Topics & Concepts

DystoniaDeep brain stimulationTrunkPhysical medicine and rehabilitationMedicineCervical dystoniaPsychologyNeuroscienceParkinson's diseaseInternal medicineDiseaseBiologyEcologyNeurological disorders and treatmentsGenetics and Neurodevelopmental DisordersRNA regulation and disease