Water-soluble AIE-active fluorescent organic nanoparticles for ratiometric detection of SO<sub>2</sub> in the mitochondria of living cells
Gai‐li Feng, Yichen Liu, Yan‐ming Ji, Wei Zhou, Xia-fen Li, Min Hou, Jie-lei Gao, Yuan Zhang, Guo‐wen Xing
Abstract
Mitochondria-targeted fluorescent organic nanoparticles (TYDLs) with a low detection limit (75 nM) were reported for the ratiometric detection of SO 2 /HSO 3 − in vitro and in vivo .
Topics & Concepts
FluorescenceDetection limitMitochondrionEndogenyChemistryNanoparticleLiving cellSelectivityAggregation-induced emissionCellBiophysicsWater solubleNanotechnologyCombinatorial chemistryBiochemistryMaterials scienceChromatographyBiologyCell biologyOrganic chemistryCatalysisOpticsPhysicsLuminescence and Fluorescent MaterialsSulfur Compounds in BiologyMolecular Sensors and Ion Detection