Litcius/Paper detail

Nanobody-engineered bispecific IL-18 mimetics drive antitumor immunity by engaging CD8+ T cell and evading IL-18BP in preclinical models

Yanyang Nan, Min Zhu, Qian Wang, Xiaoxue Du, Caili Xu, Yuping Huang, Yujie Liu, Shaoyuan Zhou, Yuluoyan Qiu, Xiao Chu, Dianwen Ju, Yakun Wan, Xuyao Zhang

2025Molecular Therapy34 citationsDOIOpen Access PDF

Topics & Concepts

Cancer researchCytotoxic T cellImmunotherapyCancer immunotherapyCD8Immune systemCytokineT cellImmunologyCell biologyBiologyChemistryIn vitroBiochemistryMonoclonal and Polyclonal Antibodies ResearchImmunotherapy and Immune ResponsesImmune Cell Function and Interaction