Specificity of SARS-CoV-2 Real-Time PCR Improved by Deep Learning Analysis
David Alouani, Roshani R. P. Rajapaksha, Mehul Jani, Daniel D. Rhoads, Navid Sadri
Abstract
Real-time PCR (RT-PCR) is widely used to diagnose human pathogens. RT-PCR data are traditionally analyzed by estimating the threshold cycle ( C T ) at which the fluorescence signal produced by emission of a probe crosses a baseline level.
Topics & Concepts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Real-time polymerase chain reactionCoronavirus disease 2019 (COVID-19)Computational biologyArtificial intelligenceSIGNAL (programming language)Computer scienceQuality assuranceInterpretation (philosophy)Biological systemBiologyStatisticsPattern recognition (psychology)VirologyMachine learningMedicineMathematicsPathologyGeneticsGeneInfectious disease (medical specialty)DiseaseExternal quality assessmentProgramming languageMolecular Biology Techniques and ApplicationsSARS-CoV-2 detection and testingDomain Adaptation and Few-Shot Learning