Litcius/Paper detail

68Ga-FAPI Uptake of Thyroiditis in a Patient With Breast Cancer

Canan Can, Cihan Gündoğan, Yunus Güzel, İhsan Kaplan, Halil Kömek

2021Clinical Nuclear Medicine37 citationsDOI

Abstract

ABSTRACT: 68Ga-fibroblast activation protein-specific inhibitor (FAPI)-04 PET/CT was performed in a 49-year-old woman diagnosed with breast cancer. In PET/CT imaging, intense 68Ga-FAPI uptake was observed in the primary tumor, axillary lymph nodes, and also in the thyroid gland, whereas pathological 18F-FDG uptake was not observed in the thyroid gland. On thyroid ultrasonography, parenchyma was heterogeneous, and an area of focal thyroiditis was observed in the superior part of the right lobe. Biochemical parameters were found to be consistent with thyroiditis. This case shows that FAPI uptake in the thyroid gland may be associated with thyroiditis and should be evaluated clinically.

Topics & Concepts

MedicineThyroidThyroiditisParenchymaPathologyLymphPathologicalBreast cancerSubacute thyroiditisThyroid cancerAxillary lymph nodesRadiologyNuclear medicineCancerInternal medicinePeptidase Inhibition and AnalysisCardiac Structural Anomalies and RepairProtease and Inhibitor Mechanisms