Recent progress in the development of small-molecule fluorescent probes for detection and imaging of selenocysteine and application in thyroid disease diagnosis

Abstract

, in terms of the cleavage of the responsive group by the SeCys nucleophile: (i) 2,4-dinitrobene sulphonamide group, (ii) 2,4-dinitrobenesulfonate ester group, (iii) 2,4-dinitrobenzeneoxy group and (iv) miscellaneous types. Overall this article deals with the analysis of more than two dozen fluorescent probes demonstrated for selective detection of SeCys along with their applications towards disease diagnosis.

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