Low-dose metronomic chemotherapy triggers oxidized mtDNA sensing inside tumor cells to potentiate CD8+T anti-tumor immunity
Wen Qiao, Cegui Hu, Jiayi Ma, Xinrui Dong, Sumiya Dalangood, Hanjun Li, Chenwei Yuan, Binbin Lu, Wei‐Qiang Gao, Zhenke Wen, Wenjin Yin, Jun Gui
Topics & Concepts
ChemotherapyCD8ChemoimmunotherapyCancer researchCytotoxic T cellImmunogenic cell deathImmune systemReactive oxygen speciesT cellBiologyMitochondrionMitochondrial ROSImmune checkpointImmunotherapyPharmacologyImmunologyCell biologyBiochemistryIn vitroGeneticsinterferon and immune responsesImmune cells in cancerImmune Cell Function and Interaction