Iodine catalyzed synthesis of imidazo[1,2- <i>a</i> ]pyrazine and imidazo[1,2- <i>a</i> ]pyridine derivatives and their anticancer activity
Rajavenkatesh Krishnamoorthy, Parthiban Anaikutti
Abstract
Herein, we present the iodine catalyzed an efficient synthesis of imidazo[1,2- a ]pyrazine and pyridine derivatives and studied their anticancer activities against in vitro cancer cell lines namely, Hep-2, HepG2, MCF-7, and A375.
Topics & Concepts
PyrazinePyridineChemistryIodineCatalysisCombinatorial chemistryCancer cell linesIn vitroMedicinal chemistryStereochemistryOrganic chemistryCancerCancer cellBiochemistryBiologyGeneticsSynthesis and biological activitySynthesis and Reactivity of HeterocyclesSynthesis and Characterization of Heterocyclic Compounds