Litcius/Paper detail

Acquired Hemophilia A Post-COVID-19 Vaccination: A Case Report and Review

Hussam Al Hennawi, Mohammad K Al Masri, Mohamad Bakir, Mohidin Barazi, Feras Jazaeri, Talal Almasri, Sami J Shoura, Abdul Rahman R Barakeh, Abdulrahman Taftafa, Muhammad Khurshid Khan, Henry I Zaleski

2022Cureus22 citationsDOIOpen Access PDF

Abstract

Acquired hemophilia A (AHA) is an inhibitory coagulopathy that represents a rare variant of hemorrhagic syndromes. We present a case of idiopathic AHA in a 75-year-old male patient with a cutaneous hematoma that could be attributed to a recent COVID-19 vaccination. The aim of this report is to raise awareness of a possible association between AHA and COVID-19 vaccination and to review similar reported cases and management plans to prevent the development of possible morbidity and debilitating complications. This case illustrates an exceptionally rare side effect of the COVID-19 vaccination. The advantages of obtaining the COVID-19 vaccine outweigh the risks.

Topics & Concepts

MedicineVaccinationCoronavirus disease 2019 (COVID-19)CoagulopathyIntensive care medicine2019-20 coronavirus outbreakPediatricsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)SurgeryImmunologyInternal medicineVirologyOutbreakDiseaseInfectious disease (medical specialty)Hemophilia Treatment and ResearchPlatelet Disorders and TreatmentsCoagulation, Bradykinin, Polyphosphates, and Angioedema