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Design, synthesis, biological evaluation of 3,5-diaryl-4,5-dihydro-1H-pyrazole carbaldehydes as non-purine xanthine oxidase inhibitors: Tracing the anticancer mechanism via xanthine oxidase inhibition

Gaurav Joshi, Manisha Sharma, Sourav Kalra, Navnath S. Gavande, Sandeep Singh, Raj Kumar

2021Bioorganic Chemistry38 citationsDOI

Topics & Concepts

Xanthine oxidaseChemistryOxidative stressReactive oxygen speciesBiochemistryHypoxanthinePurineDocking (animal)ApoptosisXanthinePurine metabolismEnzymePharmacologyBiologyMedicineNursingGout, Hyperuricemia, Uric AcidGenomics, phytochemicals, and oxidative stressGinseng Biological Effects and Applications
Design, synthesis, biological evaluation of 3,5-diaryl-4,5-dihydro-1H-pyrazole carbaldehydes as non-purine xanthine oxidase inhibitors: Tracing the anticancer mechanism via xanthine oxidase inhibition | Litcius