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Prodrugs for nitroreductase based cancer therapy-4: Towards prostate cancer targeting: Synthesis of N-heterocyclic nitro prodrugs, Ssap-NtrB enzymatic activation and anticancer evaluation

Tuğba Güngör, Esra Tokay, Ünzile Güven Gülhan, Nelin Hacıoğlu, Ayhan Çelik, Feray Köçkar, Mehmet Ay

2020Bioorganic Chemistry16 citationsDOI

Topics & Concepts

NitroreductaseProdrugChemistryProstate cancerEnzymeCancerNitroCancer therapyCancer researchPharmacologyBiochemistryCombinatorial chemistryInternal medicineMedicineOrganic chemistryAlkylSynthesis and Characterization of Heterocyclic CompoundsMXene and MAX Phase MaterialsAdenosine and Purinergic Signaling
Prodrugs for nitroreductase based cancer therapy-4: Towards prostate cancer targeting: Synthesis of N-heterocyclic nitro prodrugs, Ssap-NtrB enzymatic activation and anticancer evaluation | Litcius