Geraniin restricts inflammasome activation and macrophage pyroptosis by preventing the interaction between ASC and NLRP3 to exert anti-inflammatory effects
Xiaoyi Zhou, Minyan Qin, Leran He, Ying Zhang, Aijun Liu, Dongfeng Chen, Hao Pan
Topics & Concepts
PyroptosisInflammasomeMacrophageCaspase 1InflammationChemistryCell biologyImmunologyPharmacologyMedicineBiologyBiochemistryIn vitroInflammasome and immune disordersGout, Hyperuricemia, Uric AcidParaoxonase enzyme and polymorphisms