Antimicrobial and Anti-Inflammatory Activities of MAF-1-Derived Antimicrobial Peptide Mt6 and Its D-Enantiomer D-Mt6 against Acinetobacter baumannii by Targeting Cell Membranes and Lipopolysaccharide Interaction
Delong Kong, Xuan Hua, Rui Zhou, Jie Cui, Tao Wang, Fanyun Kong, Hongjuan You, Xiangye Liu, Joseph Adu‐Amankwaah, Guo Guo, Kuiyang Zheng, Jianwei Wu, Renxian Tang
Abstract
Around 700,000 people worldwide die each year from antibiotic-resistant pathogens. Acinetobacter baumannii in clinical specimens increases year by year, and it is developing a strong resistance to clinical drugs, which is resulting in A. baumannii becoming the main opportunistic pathogen. Antimicrobial peptides show great potential as new antibacterial drugs that can replace traditional antibiotics.
Topics & Concepts
AntimicrobialAcinetobacter baumanniiAntimicrobial peptidesBiofilmMicrobiologyBiologyAntibioticsBacteriaPseudomonas aeruginosaGeneticsAntimicrobial Peptides and ActivitiesAntibiotic Resistance in BacteriaInsect Utilization and Effects