The Rise of Manganese-Catalyzed Reduction Reactions
Christophe Werlé, Peter Schlichter
Abstract
Abstract Recent developments in manganese-catalyzed reducing transformations—hydrosilylation, hydroboration, hydrogenation, and transfer hydrogenation—are reviewed herein. Over the past half a decade (i.e., 2016 to the present), more than 115 research publications have been reported in these fields. Novel organometallic compounds and new reduction transformations have been discovered and further developed. Significant challenges that had historically acted as barriers for the use of manganese catalysts in reduction reactions are slowly being broken down. This review will hopefully assist in developing this research area, by presenting a clear and concise overview of the catalyst structures and substrate transformations published so far. 1 Introduction 2 Hydrosilylation 3 Hydroboration 4 Hydrogenation 5 Transfer Hydrogenation 6 Conclusion and Perspective