Production of γ-Aminobutyrate (GABA) in Recombinant <i>Corynebacterium glutamicum</i> by Expression of Glutamate Decarboxylase Active at Neutral pH
Jina Son, Kei‐Anne Baritugo, Yu Jung Sohn, Kyoung Hee Kang, Hee Taek Kim, Jeong Chan Joo, Si Jae Park
Abstract
glucose. The recombinant strains developed in this study could be used for the establishment of sustainable direct fermentative GABA production from renewable resources under mild culture conditions, thus increasing the availability of various GADs.
Topics & Concepts
Corynebacterium glutamicumGlutamate decarboxylaseRecombinant DNAChemistryGlutamate receptorCarboxy-lyasesBiochemistryMicrobiologyEnzymeBiologyGeneReceptorGABA and Rice ResearchMicrobial Metabolic Engineering and BioproductionProbiotics and Fermented Foods