Metformin and/or low dose radiation reduces cardiotoxicity and apoptosis induced by cyclophosphamide through SIRT-1/SOD and BAX/Bcl-2 pathways in rats
Shereen M. El kiki, Mervat M. Omran, Heba H. Mansour, Hesham Farouk Hasan
Topics & Concepts
CardiotoxicityApoptosisOxidative stressPharmacologyMetforminCardioprotectionCyclophosphamideMedicineToxicityAntioxidantChemistryNecrosisEndocrinologyChemotherapyInternal medicineDiabetes mellitusMyocardial infarctionBiochemistryChemotherapy-induced cardiotoxicity and mitigationChemotherapy-induced organ toxicity mitigationCancer-related cognitive impairment studies