Experimental Variables that Affect Human Hepatocyte AAV Transduction in Liver Chimeric Mice
Chenhui Zou, Koen Vercauteren, Eleftherios Michailidis, Mohammad Kabbani, Irene Zoluthkin, Corrine Quirk, Luis Chiriboga, Mustafa N. Yazicioglu, Xavier M. Anguela, Philip Meuleman, Katherine A. High, Roland W. Herzog, Ype P. de Jong
Abstract
chimera model, attention to which may improve reproducibility between findings from different laboratories.
Topics & Concepts
Transduction (biophysics)TransgeneBiologyHepatocyteGenetic enhancementAdeno-associated virusViral vectorSignal transductionCell biologyGreen fluorescent proteinMolecular biologyGeneVirologyVector (molecular biology)GeneticsIn vitroRecombinant DNABiochemistryVirus-based gene therapy researchViral Infectious Diseases and Gene Expression in InsectsViral gastroenteritis research and epidemiology