Induced, but not natural, regulatory T cells retain phenotype and function following exposure to inflamed synovial fibroblasts
Sujuan Yang, Ximei Zhang, Jingrong Chen, Junlong Dang, Rongzhen Liang, Donglan Zeng, Huan Zhang, Youqiu Xue, Yan Liu, Wenbin Wu, Jun Zhao, Julie Wang, Yunfeng Pan, Hanshi Xu, Bing Sun, Feng Huang, Yan Lü, Willa A. Hsueh, Nancy J. Olsen, Song Guo Zheng
Abstract
Induced regulatory T cells are phenotypic and functionally stable when encountering inflamed synovial fibroblast.
Topics & Concepts
FOXP3ImmunologyIn vivoCytokineRheumatoid arthritisArthritisIn vitroPathogenesisStimulationPhenotypeInflammationSynovial membraneMedicineAutoimmune diseaseCancer researchBiologyImmune systemAntibodyInternal medicineGeneBiochemistryBiotechnologyT-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune Responses