Development and validation of a UPLC-MS/MS method for simultaneous quantification of levofloxacin, ciprofloxacin, moxifloxacin and rifampicin in human plasma: Application to the therapeutic drug monitoring in osteoarticular infections
B Llopis, Christian Funck‐Brentano, Nadine Tissot, Alexandre Bleibtreu, Stéphane Jauréguiberry, É. Fourniols, Alexandra Aubry, Noël Zahr
Topics & Concepts
ChemistryMoxifloxacinChromatographyProtein precipitationFormic acidRifampicinTherapeutic drug monitoringAntibacterial agentLevofloxacinTandem mass spectrometryHigh-performance liquid chromatographyPharmacokineticsMass spectrometryAntibioticsPharmacologyBiochemistryMedicineAntibiotics Pharmacokinetics and EfficacyOrthopedic Infections and TreatmentsBacterial Identification and Susceptibility Testing