Highly Efficient and Stable Atomically Dispersed Cu Catalyst for Azide‐Alkyne Cycloaddition Reaction
Peng Ren, Qinglin Li, Tao Song, Zhaozhan Wang, Ken Motokura, Yong Yang
Abstract
Abstract In this study, we report a highly stable and efficient single‐atom Cu dispersed on N‐doped porous carbon as a superior catalyst for azide‐alkyne cycloaddition reaction. A broad set of 1,4‐disubstituted 1,2,3‐triazoles was synthesized in high to excellent yields with good tolerance of various functional groups in a cost‐effective, environment‐friendly manner. Parallel studies show that the single‐atom Cu with unique coordination structure exhibits superior catalytic activity to the metallic Cu nanoparticles analogue. Remarkably, the single‐atom Cu catalyst demonstrates robust stability and can be reused several times without variations in activity and regioselectivity.