Smoking and tetramer tryptase accelerate intervertebral disc degeneration by inducing METTL14-mediated DIXDC1 m6 modification
Ji Tu, Wentian Li, Philip M. Hansbro, Yan Qi, Xupeng Bai, Chantal Donovan, Richard Kim, Izabela Galvão, Abhirup Das, Yang Cao, Jun Zou, Ashish D. Diwan
Topics & Concepts
Intervertebral discDegeneration (medical)Wnt signaling pathwayMedicineCancer researchProteasesCell biologyFrizzledBiologyChemistryPathologySignal transductionAnatomyBiochemistryEnzymeCancer-related gene regulationRNA modifications and cancerPeroxisome Proliferator-Activated Receptors