The Effects of Drug Addiction and Detoxification on the Human Oral Microbiota
Jun Zhang, Wenli Liu, Linyu Shi, Xu Liu, Mengchun Wang, Wanting Li, Daijing Yu, Yaya Wang, Jingjing Zhang, Keming Yun, Jiangwei Yan
Abstract
Drug addiction has serious negative consequences for human health and public security. The evidence indicates that drug abuse can cause poor oral health. In the current study, we observed that drug addiction caused oral microbial dysbiosis. Detoxication have positive effects on the recovery of oral microbial community structures to some extent. Understanding the effects of drug addiction and detoxification on oral microbial communities will promote a more rational approach for recovering the oral function and health of drug users. Furthermore, specific microbial species might be considered biomarkers that could provide information regarding drug abuse status for saliva left at crime scenes. To the best of our knowledge, this is the first report on the role of the oral microbiota in drug addiction and detoxification. Our findings give new clues to understand the association between drug addiction and oral health.