Impact of NDI‐Core Substitution on the pH‐Responsive Nature of Peptide‐Tethered Luminescent Supramolecular Polymers
Aritra Sarkar, Jonas C. Kölsch, Christian M. Berač, Akhil Venugopal, Ranjan Sasmal, Ronja Otter, Pol Besenius, Subi J. George
Abstract
The pH-responsive nature of two self-assembled NDI-peptide amphiphile conjugates is reported. The diethoxy substituted NDI showed a pH-dependent assembly behaviour, as expected. In contrast, the isopropylamino- and ethoxy-substituted NDI based supramolecular polymer was stable at acidic and basic aqueous conditions. This finding highlights how subtle changes in the molecular design of π-stacked chromophore-peptide conjugates have a drastic impact on their equilibrium structure and ultimately functional properties.
Topics & Concepts
Supramolecular chemistryPeptideAmphiphileChemistryChromophoreConjugateAqueous solutionAlkoxy groupSupramolecular polymersPolymerLuminescenceCombinatorial chemistrySubstitution (logic)StereochemistryCopolymerMoleculeOrganic chemistryMaterials scienceAlkylBiochemistryComputer scienceMathematical analysisOptoelectronicsMathematicsProgramming languageSupramolecular Self-Assembly in MaterialsPolydiacetylene-based materials and applicationsMetal-Organic Frameworks: Synthesis and Applications