<i>Toxoplasma gondii</i> Toxolysin 4 Contributes to Efficient Parasite Egress from Host Cells
My‐Hang Huynh, Marijo S. Roiko, Angélica Oliveira Gomes, Ellyn N. Schinke, Aric J. Schultz, Swati Agrawal, Christine A. Oellig, Travis Sexton, Jessica M. Beauchamp, Julie Laliberté, Komagal Kannan Sivaraman, Louis B. Hersh, Sheena McGowan, Vern B. Carruthers
Abstract
After replicating within infected host cells, the single-celled parasite Toxoplasma gondii must rupture out of such cells in a process termed egress. Although it is known that T. gondii egress is an active event that involves disruption of host-derived membranes surrounding the parasite, very few proteins that are released by the parasite are known to facilitate egress.
Topics & Concepts
Toxoplasma gondiiMicronemeBiologyParasite hostingLytic cycleCell biologyProteasesMicrobiologyGeneticsAntibodyApicomplexaImmunologyMalariaEnzymePlasmodium falciparumWorld Wide WebVirusComputer scienceBiochemistryToxoplasma gondii Research StudiesParasitic Infections and DiagnosticsCytomegalovirus and herpesvirus research