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The genetic background significantly impacts the severity of kidney cystic disease in the Pkd1RC/RC mouse model of autosomal dominant polycystic kidney disease

Jennifer Arroyo, Diana Escobar-Zarate, Harrison H. Wells, Megan Constans, Ka Thao, Jessica M. Smith, Cynthia J. Sieben, Madeline R. Martell, Timothy L. Kline, María V. Irazabal, Vicente E. Torres, Katharina Hopp, Peter C. Harris

2021Kidney International57 citationsDOIOpen Access PDF

Topics & Concepts

PKD1Autosomal dominant polycystic kidney diseaseTolvaptanKidney diseaseKidneyPolycystic kidney diseaseInternal medicineMedicinePathogenesisEndocrinologyCystDiseaseAutosomal Recessive Polycystic Kidney DiseaseBiologyPathologyRenal functionGastroenterologyHeart failureGenetic and Kidney Cyst DiseasesRenal and related cancersPediatric Urology and Nephrology Studies
The genetic background significantly impacts the severity of kidney cystic disease in the Pkd1RC/RC mouse model of autosomal dominant polycystic kidney disease | Litcius