Photocleavable core cross-linked polymeric micelles of polypept(o)ides and ruthenium(<scp>ii</scp>) complexes
Tobias Bauer, Jonas Eckrich, Nadine Wiesmann, Felix Kuczelinis, Wen Sun, Xiaolong Zeng, Benjamin Weber, Si Wu, Nicolas H. Bings, Sebastian Strieth, Matthias Barz
Abstract
Functional polypept(o)ides and ruthenium( ii ) complexes are combined in photocleavable core cross-linked micelles for colloidal stability. Irradiation-induced cleavage releases the ruthenium pro-drugs and provides spatial resolution to drug delivery.
Topics & Concepts
RutheniumMicelleCore (optical fiber)Materials sciencePolymer chemistryChemical engineeringCombinatorial chemistryChemistryOrganic chemistryCatalysisAqueous solutionComposite materialEngineeringAdvanced Polymer Synthesis and CharacterizationPhotochromic and Fluorescence ChemistryPorphyrin and Phthalocyanine Chemistry