Litcius/Paper detail

Synergistic lethality between auranofin-induced oxidative DNA damage and ATR inhibition in cancer cells

Zhang Shan, Yue Zhao, Xueqi Wang, Ce Qi, Jialiang Tian, Zhihua Zou

2023Life Sciences13 citationsDOI

Topics & Concepts

AuranofinLethalityDNA damageSynthetic lethalityOxidative damageChemistryOxidative phosphorylationOxidative stressCancer cellDNA repairDNACancer researchCancerPharmacologyBiologyBiochemistryToxicologyGeneticsImmunologyRheumatoid arthritisDNA Repair MechanismsRedox biology and oxidative stressCarcinogens and Genotoxicity Assessment